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What a 400-Meter Walk Reveals

An exercise-and-nutrition trial found fewer mobility-loss events in a frail older group. More falls complicated the result.

8 Nov 2026 3 min read

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Longevity

Old Blood Cells Reveal a Slower Route to Cellular Rejuvenation

Bonn researchers tracked aging marks as blood precursors became neural stem cells. The slow reset offers a way to study rejuvenation, with important limits to the headline numbers.

22 Oct 2026 9 min read

Longevity

Aging Mice Had Immune Cells in Their Tumors. The Defense Still Faltered.

In middle-aged male mice, researchers traced part of a weaker cancer response to lymph nodes. The local supply of T cells available for a new response had shrunk.

10 Oct 2026 3 min read

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Longevity

ER-100 has human data. What do three patients show?

Three glaucoma patients, 56 days and an early visual-field signal: ER-100 has moved beyond its first dose, but not into proof of rejuvenation.

8 Oct 2026 2 min read

Longevity

The Immune System May Remodel Instead of Simply Fading

People past 100 had expanded clones of cytotoxic CD4 T cells. The pattern suggests adaptation to persistent threats, not proof that the cells cause longevity.

3 Oct 2026 3 min read

Longevity

Old cells leave a chemical fingerprint

RamanOmics links light-scattering chemistry to gene activity in aged mouse lung and skin. A shared lipid signal may help locate senescent cells without pretending they are one uniform target.

22 Sep 2026 3 min read

Longevity

Your organs do not age on one clock

An analysis of 25,306 tissue slides maps nonlinear structural change across 40 human tissues. It is a research framework—not a personal age test or proof that every observed change is damage.

21 Sep 2026 4 min read

Longevity

Semaglutide Extended Lifespan in Mice. What Did It Prove?

Ninety-two days draws attention. Keeping three mouse experiments and two human studies separate reveals what the result can actually tell us.

Reality Check 5 Sep 2026 4 min read

Longevity

Human Senescence Atlas Turns Aging Into a Mapping Problem

NIH's SenNet atlas does not prove an anti-aging therapy. It gives longevity science a harder measurement layer.

18 Jun 2026 6 min read

Longevity

David Sinclair's XPRIZE Rejuvenation Plan Has a Proof Problem

The real story is not another anti-aging pill claim. It is whether whole-body rejuvenation can survive XPRIZE's measurement machine.

Reality Check 11 Jun 2026 5 min read

Longevity

ER-100 First Human Dosed: The Rejuvenation Test Has Left the Lab

The first human dosing of ER-100 does not prove age reversal. It starts the evidence clock for one of longevity's boldest ideas.

10 Jun 2026 5 min read

Longevity

Semaglutide Failed in Alzheimer's. The Bigger Lesson Is About Evidence.

Two major Alzheimer's trials showed semaglutide did not slow clinical decline. The result is a hard lesson in what evidence can and cannot prove.

2 Jun 2026 6 min read

Explore longevity

What a 400-Meter Walk Reveals

Old Blood Cells Reveal a Slower Route to Cellular Rejuvenation

Aging Mice Had Immune Cells in Their Tumors. The Defense Still Faltered.

Latest in Longevity

ER-100 has human data. What do three patients show?

The Immune System May Remodel Instead of Simply Fading

Old cells leave a chemical fingerprint

Your organs do not age on one clock

Semaglutide Extended Lifespan in Mice. What Did It Prove?

Human Senescence Atlas Turns Aging Into a Mapping Problem

David Sinclair's XPRIZE Rejuvenation Plan Has a Proof Problem

ER-100 First Human Dosed: The Rejuvenation Test Has Left the Lab

Semaglutide Failed in Alzheimer's. The Bigger Lesson Is About Evidence.

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